Diverse anti-NMDAR autoantibodies from individuals with encephalitis
Zoe Jamet, Frederic Villega, Laurent Groc
Nat Struct Mol Biol. 2024-11-27
10.1038/s41594-024-01435-y

Ketamine alleviates NMDA receptor hypofunction through synaptic trapping
Frédéric Villéga, Alexandra Fernandes, Julie Jézéquel, Floriane Uyttersprot, Nathan Benac, Sarra Zenagui, Laurine Bastardo, Hélène Gréa, Delphine Bouchet, Léa Villetelle, Olivier Nicole, Véronique Rogemond, Jérôme Honnorat, Julien P. Dupuis, Laurent Groc
Neuron. 2024-10-01
10.1016/j.neuron.2024.06.028

Synaptic rearrangement of NMDA receptors controls memory engram formation and malleability in the cortex
Benjamin Bessières, Julien Dupuis, Laurent Groc, Bruno Bontempi, Olivier Nicole
Sci. Adv.. 2024-08-30
10.1126/sciadv.ado1148

APP fragment controls both ionotropic and non-ionotropic signaling of NMDA receptors
Jade Dunot, Sebastien Moreno, Carine Gandin, Paula A. Pousinha, Mascia Amici, Julien Dupuis, Margarita Anisimova, Alex Winschel, Magalie Uriot, Samuel J. Petshow, Maria Mensch, Ingrid Bethus, Camilla Giudici, Heike Hampel, Benedikt Wefers, Wolfgang Wurst, Ronald Naumann, Michael C. Ashby, Bodo Laube, Karen Zito, Jack R. Mellor, Laurent Groc, Michael Willem, Hélène Marie
Neuron. 2024-06-01
10.1016/j.neuron.2024.05.027

NMDA receptor autoantibodies primarily impair the extrasynaptic compartment
Zoe Jamet, Camille Mergaux, Morgane Meras, Delphine Bouchet, Frédéric Villega, Jakob Kreye, Harald Prüss, Laurent Groc
Brain. 2024-05-17
10.1093/BRAIN/AWAE163

Converging synaptic and network dysfunctions in distinct autoimmune encephalitis
Daniel Hunter, Mar Petit-Pedrol, Dominique Fernandes, Nathan Bénac, Catarina Rodrigues, Jakob Kreye, Mihai Ceanga, Harald Prüss, Christian Geis, Laurent Groc
EMBO Rep. 2024-01-22
10.1038/s44319-024-00056-2

Non-canonical interplay between glutamatergic NMDA and dopamine receptors shapes synaptogenesis
Nathan Bénac, G. Ezequiel Saraceno, Corey Butler, Nahoko Kuga, Yuya Nishimura, Taiki Yokoi, Ping Su, Takuya Sasaki, Mar Petit-Pedrol, Rémi Galland, Vincent Studer, Fang Liu, Yuji Ikegaya, Jean-Baptiste Sibarita, Laurent Groc
Nat Commun. 2024-01-02
10.1038/s41467-023-44301-z

Surface Glutamate Receptor Nanoscale Organization with Super-Resolution Microscopy (dSTORM)
Joana Ferreira, Laurent Groc
Neuromethods. 2024-01-01
https://www.bordeaux-neurocampus.fr/11492

GluN3A subunit tunes NMDA receptor synaptic trafficking and content during postnatal brain development
Inmaculada M. González-González, John A. Gray, Joana Ferreira, María Jose Conde-Dusman, Delphine Bouchet, Isabel Perez-Otaño, Laurent Groc
Cell Reports. 2023-05-01
10.1016/j.celrep.2023.112477

Nanoscale and functional heterogeneity of the hippocampal extracellular space
Diego Grassi, Agata Idziak, Antony Lee, Ivo Calaresu, Jean-Baptiste Sibarita, Laurent Cognet, U. Valentin Nägerl, Laurent Groc
Cell Reports. 2023-05-01
10.1016/j.celrep.2023.112478

Cognitive and psychiatric features of anti-NMDA receptor encephalitis
Frederic Villéga, Harald Prüss, Ludger Tebartz van Elst, Laurent Groc
The Lancet Neurology. 2022-10-01
10.1016/S1474-4422(22)00349-0

Near-Infrared Carbon Nanotube Tracking Reveals the Nanoscale Extracellular Space around Synapses
Chiara Paviolo, Joana S. Ferreira, Antony Lee, Daniel Hunter, Ivo Calaresu, Somen Nandi, Laurent Groc, Laurent Cognet
Nano Lett.. 2022-08-29
10.1021/acs.nanolett.1c04259

Multi-Dimensional Spectral Single Molecule Localization Microscopy
Corey Butler, G Ezequiel Saraceno, Adel Kechkar, Nathan Bénac, Vincent Studer, Julien P. Dupuis, Laurent Groc, Rémi Galland, Jean-Baptiste Sibarita
Front. Bioinform.. 2022-03-04
10.3389/fbinf.2022.813494

CaMKII activation persistently segregates postsynaptic proteins via liquid phase separation
Tomohisa Hosokawa, Pin-Wu Liu, Qixu Cai, Joana S. Ferreira, Florian Levet, Corey Butler, Jean-Baptiste Sibarita, Daniel Choquet, Laurent Groc, Eric Hosy, Mingjie Zhang, Yasunori Hayashi
Nat Neurosci. 2021-04-29
10.1038/s41593-021-00843-3

A Bottom-Up Approach to Red-Emitting Molecular-Based Nanoparticles with Natural Stealth Properties and their Use for Single-Particle Tracking Deep in Brain Tissue.
Rosendale M, Flores J, Paviolo C, Pagano P, Daniel J, Ferreira J, Verlhac JB, Groc L, Cognet L, Blanchard-Desce M.
Advanced Materialds. 2021-04-21
10.1002/adma.202006644

Regulation of membrane NMDA receptors by dynamics and protein interactions
Mar Petit-Pedrol, Laurent Groc
Journal of Cell Biology. 2020-12-18
10.1083/jcb.202006101

CaMKII activation triggers persistent formation and segregation of postsynaptic liquid phase
Tomohisa Hosokawa, Pin-Wu Liu, Qixu Cai, Joana S. Ferreira, Florian Levet, Corey Butler, Jean-Baptiste Sibarita, Daniel Choquet, Laurent Groc, Eric Hosy, Mingjie Zhang, Yasunori Hayashi
. 2020-11-26
10.1101/2020.11.25.397091

Distance-dependent regulation of NMDAR nanoscale organization along hippocampal neuron dendrites
Joana S. Ferreira, Julien P. Dupuis, Blanka Kellermayer, Nathan Bénac, Constance Manso, Delphine Bouchet, Florian Levet, Corey Butler, Jean-Baptiste Sibarita, Laurent Groc
Proc Natl Acad Sci USA. 2020-09-14
10.1073/pnas.1922477117

Synucleinopathy alters nanoscale organization and diffusion in the brain extracellular space through hyaluronan remodeling
Federico N. Soria, Chiara Paviolo, Evelyne Doudnikoff, Marie-Laure Arotcarena, Antony Lee, Noémie Danné, Amit Kumar Mandal, Philippe Gosset, Benjamin Dehay, Laurent Groc, Laurent Cognet, Erwan Bezard
Nat Commun. 2020-07-10
10.1038/s41467-020-17328-9

Human endogenous retroviral protein triggers deficit in glutamate synapse maturation and behaviors associated with psychosis
E. M. Johansson, D. Bouchet, R. Tamouza, P. Ellul, AS. Morr, E. Avignone, R. Germi, M. Leboyer, H. Perron, L. Groc
Sci. Adv.. 2020-07-01
10.1126/sciadv.abc0708

Linking glutamate receptor movements and synapse function
Laurent Groc, Daniel Choquet
Science. 2020-06-11
10.1126/science.aay4631

Fluorescent sp3 Defect-Tailored Carbon Nanotubes Enable NIR-II Single Particle Imaging in Live Brain Slices at Ultra-Low Excitation Doses
Amit Kumar Mandal, Xiaojian Wu, Joana S. Ferreira, Mijin Kim, Lyndsey R. Powell, Hyejin Kwon, Laurent Groc, YuHuang Wang, Laurent Cognet
Sci Rep. 2020-03-24
10.1038/s41598-020-62201-w

Aquaporin-4 Surface Trafficking Regulates Astrocytic Process Motility and Synaptic Activity in Health and Autoimmune Disease.
Silvia Ciappelloni, Delphine Bouchet, Nadège Dubourdieu, Eric Boué-Grabot, Blanka Kellermayer, Constance Manso, Romain Marignier, Stéphane H.R. Oliet, Thomas Tourdias, Laurent Groc
Cell Reports. 2019-06-01
10.1016/j.celrep.2019.05.097

Self-Interference (SELFI) Microscopy for Live Super-Resolution Imaging and Single Particle Tracking in 3D
Jeanne Linarès-Loyez, Joana S. Ferreira, Olivier Rossier, Brahim Lounis, Gregory Giannone, Laurent Groc, Laurent Cognet, Pierre Bon
Front. Phys.. 2019-05-08
10.3389/fphy.2019.00068

Surface trafficking of neurotransmitter receptors: From cultured neurons to intact brain preparations
Julien P. Dupuis, Laurent Groc
Neuropharmacology. 2019-05-01
10.1016/j.neuropharm.2019.05.019

Nanoscale exploration of the extracellular space in the live brain by combining single carbon nanotube tracking and super-resolution imaging analysis
Chiara Paviolo, Federico N. Soria, Joana S. Ferreira, Antony Lee, Laurent Groc, Erwan Bezard, Laurent Cognet
Methods. 2019-03-09
10.1016/j.ymeth.2019.03.005

Differential Nanoscale Topography and Functional Role of GluN2-NMDA Receptor Subtypes at Glutamatergic Synapses
Blanka Kellermayer, Joana S. Ferreira, Julien Dupuis, Florian Levet, Dolors Grillo-Bosch, Lucie Bard, Jeanne Linarès-Loyez, Delphine Bouchet, Daniel Choquet, Dmitri A. Rusakov, Pierre Bon, Jean-Baptiste Sibarita, Laurent Cognet, Matthieu Sainlos, Ana Luisa Carvalho, Laurent Groc
Neuron. 2018-10-01
10.1016/j.neuron.2018.09.012

Pathogenicity of Antibodies against NMDA Receptor: Molecular Insights into Autoimmune Psychosis.
J. Jézéquel, E.M. Johansson, M. Leboyer, L. Groc
Trends in Neurosciences. 2018-08-01
10.1016/j.tins.2018.05.002

Dynamic disorganization of synaptic NMDA receptors triggered by autoantibodies from psychotic patients
Julie Jézéquel, Emily M. Johansson, Julien P. Dupuis, Véronique Rogemond, Hélène Gréa, Blanka Kellermayer, Nora Hamdani, Emmanuel Le Guen, Corentin Rabu, Marilyn Lepleux, Marianna Spatola, Elodie Mathias, Delphine Bouchet, Amy J. Ramsey, Robert H. Yolken, Ryad Tamouza, Josep Dalmau, Jérôme Honnorat, Marion Leboyer, Laurent Groc
Nat Commun. 2017-11-27
10.1038/s41467-017-01700-3

Dynamics of surface neurotransmitter receptors and transporters in glial cells: Single molecule insights
Silvia Ciappelloni, Ciaran Murphy-Royal, Julien P. Dupuis, Stéphane H.R. Oliet, Laurent Groc
Cell Calcium. 2017-11-01
10.1016/j.ceca.2017.08.009

Altered surface mGluR5 dynamics provoke synaptic NMDAR dysfunction and cognitive defects in Fmr1 knockout mice
Elisabetta Aloisi, Katy Le Corf, Julien Dupuis, Pei Zhang, Melanie Ginger, Virginie Labrousse, Michela Spatuzza, Matthias Georg Haberl, Lara Costa, Ryuichi Shigemoto, Anke Tappe-Theodor, Filippo Drago, Pier Vincenzo Piazza, Christophe Mulle, Laurent Groc, Lucia Ciranna, Maria Vincenza Catania, Andreas Frick
Nat Commun. 2017-10-24
10.1038/s41467-017-01191-2

Single nanoparticle tracking: A method for investigating the surface dynamics of glutamate receptors
Julien Dupuis, François Maingret, Laurent Groc
Neuromethods. 2017-09-22
10.1007/978-1-4939-7228-9_2

Co-agonists differentially tune GluN2B-NMDA receptor trafficking at hippocampal synapses
Joana S Ferreira, Thomas Papouin, Laurent Ladépêche, Andrea Yao, Valentin C Langlais, Delphine Bouchet, Jérôme Dulong, Jean-Pierre Mothet, Silvia Sacchi, Loredano Pollegioni, Pierre Paoletti, Stéphane Henri Richard Oliet, Laurent Groc
eLife. 2017-06-09
10.7554/eLife.25492

Astroglial glutamate transporters in the brain: Regulating neurotransmitter homeostasis and synaptic transmission
Ciaran Murphy-Royal, Julien Dupuis, Laurent Groc, Stéphane H. R. Oliet
Journal of Neuroscience Research. 2017-02-02
10.1002/jnr.24029

Single-nanotube tracking reveals the nanoscale organization of the extracellular space in the live brain
Antoine G. Godin, Juan A. Varela, Zhenghong Gao, Noémie Danné, Julien P. Dupuis, Brahim Lounis, Laurent Groc, Laurent Cognet
Nature Nanotech. 2016-11-21
10.1038/nnano.2016.248

Co-activation of VEGF and NMDA receptors promotes synaptic targeting of AMPA receptors
P De Rossi, E Harde, J P Dupuis, L Martin, N Chounlamountri, M Bardin, C Watrin, C Benetollo, K Pernet-Gallay, H J Luhmann, J Honnorat, G Malleret, L Groc, A Acker-Palmer, P A Salin, C Meissirel
Mol Psychiatry. 2016-11-16
10.1038/mp.2016.215

Single nanoparticle tracking of N-methyl-D-aspartate receptors in cultured and intact brain tissue
Varela JA, Ferreira JS, Dupuis JP, Durand P, Bouchet D, Groc L.
Neurophotonics. 2016-07-12
10.1117/1.NPh.3.4.041808]

Targeting neurotransmitter receptors with nanoparticles in vivo allows single-molecule tracking in acute brain slices
Juan A. Varela, Julien P. Dupuis, Laetitia Etchepare, Agnès Espana, Laurent Cognet, Laurent Groc
Nat Commun. 2016-03-14
10.1038/ncomms10947

Single nanoparticle tracking of surface ion channels and receptors in brain cells
Juan Varela, Julien Dupuis, Laurent Groc
Neuromethods. 2016-01-01
10.1007/978-1-4939-3064-7_5

Surface dynamics of GluN2B-NMDA receptors controls plasticity of maturing glutamate synapses
J. P. Dupuis, L. Ladepeche, H. Seth, L. Bard, J. Varela, L. Mikasova, D. Bouchet, V. Rogemond, J. Honnorat, E. Hanse, L. Groc
The EMBO Journal. 2014-03-03
10.1002/embj.201386356

Surface trafficking of NMDA receptors: Gathering from a partner to another
Laurent Ladépêche, Julien Pierre Dupuis, Laurent Groc
Seminars in Cell & Developmental Biology. 2014-03-01
10.1016/j.semcdb.2013.10.005

Regulation of AMPA receptor surface trafficking and synaptic plasticity by a cognitive enhancer and antidepressant molecule
H Zhang, L-A Etherington, A-S Hafner, D Belelli, F Coussen, P Delagrange, F Chaouloff, M Spedding, J J Lambert, D Choquet, L Groc
Mol Psychiatry. 2012-06-26
10.1038/mp.2012.80

Temporal modulation of hippocampal excitatory transmission by corticosteroids and stress
Francis Chaouloff, Laurent Groc
Frontiers in Neuroendocrinology. 2011-01-01
10.1016/j.yfrne.2010.07.004

Stress, corticosteroids and excitatory neurotransmission
Laurent Groc, Francis Chaouloff
Future Neurology. 2008-11-01
10.2217/14796708.3.6.623

New insights in stress-induced synaptic adaptations,Axe corticotrope et plasticité de la communication neuronale: Décryptage des mécanismes cellulaires
Laurent Groc, Francis Chaouloff
Med Sci (Paris). 2008-08-01
10.1051/medsci/20082489776

Surface trafficking of neurotransmitter receptor: comparison between single-molecule/quantum dot strategies
Groc L, Lafourcade M, Heine M, Renner M, Racine V, Sibarita JB, Lounis B, Choquet D, Cognet L.
J Neurosci.. 2007 Nov 14
27/46/12433 [pii]10.1523/JNEUROSCI.3349-07.2007

Lateral diffusion of excitatory neurotransmitter receptors during synaptogenesis
Laurent Groc, Martin Heine, Laurent Cognet, Brahim Lounis, Daniel Choquet
Molecular Mechanisms of Synaptogenesis.
10.1007/978-0-387-32562-0_16