Celebrating the Birthday of AMPA Receptor Nanodomains: Illuminating the Nanoscale Organization of Excitatory Synapses with 10 Nanocandles
Yuko Fukata, Masaki Fukata, Harold D. MacGillavry, Deepak Nair, Eric Hosy
J. Neurosci.. 2024-06-05
10.1523/JNEUROSCI.2104-23.2024

Engineering paralog-specific PSD-95 recombinant binders as minimally interfering multimodal probes for advanced imaging techniques
Charlotte Rimbault, Christelle Breillat, Benjamin Compans, Estelle Toulmé, Filipe Nunes Vicente, Monica Fernandez-Monreal, Patrice Mascalchi, Camille Genuer, Virginia Puente-Muñoz, Isabel Gauthereau, Eric Hosy, Stéphane Claverol, Gregory Giannone, Ingrid Chamma, Cameron D Mackereth, Christel Poujol, Daniel Choquet, Matthieu Sainlos
eLife. 2024-01-03
10.7554/eLife.69620

Non-autonomous stomatal control by pavement cell turgor via the K+ channel subunit AtKC1
Manuel Nieves-Cordones, Farrukh Azeem, Yuchen Long, Martin Boeglin, Geoffrey Duby, Karine Mouline, Eric Hosy, Alain Vavasseur, Isabelle Chérel, Thierry Simonneau, Frédéric Gaymard, Jeffrey Leung, Isabelle Gaillard, Jean-Baptiste Thibaud, Anne-Aliénor Véry, Arezki Boudaoud, Hervé Sentenac
The Plant Cell. 2022-02-14
10.1093/plcell/koac038

NMDAR-dependent long-term depression is associated with increased short term plasticity through autophagy mediated loss of PSD-95
Benjamin Compans, Come Camus, Emmanouela Kallergi, Silvia Sposini, Magalie Martineau, Corey Butler, Adel Kechkar, Remco V. Klaassen, Natacha Retailleau, Terrence J. Sejnowski, August B. Smit, Jean-Baptiste Sibarita, Thomas M. Bartol, David Perrais, Vassiliki Nikoletopoulou, Daniel Choquet, Eric Hosy
Nat Commun. 2021-05-14
10.1038/s41467-021-23133-9

CaMKII activation persistently segregates postsynaptic proteins via liquid phase separation
Tomohisa Hosokawa, Pin-Wu Liu, Qixu Cai, Joana S. Ferreira, Florian Levet, Corey Butler, Jean-Baptiste Sibarita, Daniel Choquet, Laurent Groc, Eric Hosy, Mingjie Zhang, Yasunori Hayashi
Nat Neurosci. 2021-04-29
10.1038/s41593-021-00843-3

Engineering paralog-specific PSD-95 synthetic binders as potent and minimally invasive imaging probes
Charlotte Rimbault, Christelle Breillat, Benjamin Compans, Estelle Toulmé, Filipe Nunes Vicente, Monica Fernandez-Monreal, Patrice Mascalchi, Camille Genuer, Virginia Puente-Muñoz, Isabel Gauthereau, Eric Hosy, Gregory Giannone, Ingrid Chamma, Cameron D. Mackereth, Christel Poujol, Daniel Choquet, Matthieu Sainlos
. 2021-04-08
10.1101/2021.04.07.438431

CaMKII activation triggers persistent formation and segregation of postsynaptic liquid phase
Tomohisa Hosokawa, Pin-Wu Liu, Qixu Cai, Joana S. Ferreira, Florian Levet, Corey Butler, Jean-Baptiste Sibarita, Daniel Choquet, Laurent Groc, Eric Hosy, Mingjie Zhang, Yasunori Hayashi
. 2020-11-26
10.1101/2020.11.25.397091

AMPA receptor nanoscale dynamic organization and synaptic plasticities
Daniel Choquet, Eric Hosy
Current Opinion in Neurobiology. 2020-08-01
10.1016/j.conb.2020.04.003

Nanoscale co-organization and coactivation of AMPAR, NMDAR, and mGluR at excitatory synapses
Julia Goncalves, Tomas M. Bartol, Côme Camus, Florian Levet, Ana Paula Menegolla, Terrence J. Sejnowski, Jean-Baptiste Sibarita, Michel Vivaudou, Daniel Choquet, Eric Hosy
Proc Natl Acad Sci USA. 2020-06-08
10.1073/pnas.1922563117

A Discrete Presynaptic Vesicle Cycle for Neuromodulator Receptors
Damien Jullié, Miriam Stoeber, Jean-Baptiste Sibarita, Hanna L. Zieger, Thomas M. Bartol, Seksiri Arttamangkul, Terrence J. Sejnowski, Eric Hosy, Mark von Zastrow
Neuron. 2020-02-01
10.1016/j.neuron.2019.11.016

A super-resolution platform for correlative live single-molecule imaging and STED microscopy
V. V. G. Krishna Inavalli, Martin O. Lenz, Corey Butler, Julie Angibaud, Benjamin Compans, Florian Levet, Jan Tønnesen, Olivier Rossier, Gregory Giannone, Olivier Thoumine, Eric Hosy, Daniel Choquet, Jean-Baptiste Sibarita, U. Valentin Nägerl
Nat Methods. 2019-10-21
10.1038/s41592-019-0611-8

TSPAN5 Enriched Microdomains Provide a Platform for Dendritic Spine Maturation through Neuroligin-1 Clustering
Edoardo Moretto, Anna Longatti, Luca Murru, Ingrid Chamma, Alessandro Sessa, Jonathan Zapata, Eric Hosy, Matthieu Sainlos, Julien Saint-Pol, Eric Rubinstein, Daniel Choquet, Vania Broccoli, Giampietro Schiavo, Olivier Thoumine, Maria Passafaro
Cell Reports. 2019-10-01
10.1016/j.celrep.2019.09.051

Pre-post synaptic alignment through neuroligin-1 tunes synaptic transmission efficiency
Kalina T Haas, Benjamin Compans, Mathieu Letellier, Thomas M Bartol, Dolors Grillo-Bosch, Terrence J Sejnowski, Matthieu Sainlos, Daniel Choquet, Olivier Thoumine, Eric Hosy
eLife. 2018-07-25
10.7554/eLife.31755

Hippocampal LTP and contextual learning require surface diffusion of AMPA receptors.
A. C. Penn, C. L. Zhang, F. Georges, L. Royer, C. Breillat, E. Hosy, J. D. Petersen, Y. Humeau, D. Choquet
Nature. 2017-09-13
10.1038/nature23658

Structural basis for plant plasma membrane protein dynamics and organization into functional nanodomains.
Julien Gronnier, Jean-Marc Crowet, Birgit Habenstein, Mehmet Nail Nasir, Vincent Bayle, Eric Hosy, Matthieu Pierre Platre, Paul Gouguet, Sylvain Raffaele, Denis Martinez, Axelle Grelard, Antoine Loquet, Françoise Simon-Plas, Patricia Gerbeau-Pissot, Christophe Der, Emmanuelle M Bayer, Yvon Jaillais, Magali Deleu, Véronique Germain, Laurence Lins, Sébastien Mongrand
eLife. 2017-07-31
10.7554/elife.26404

Review on the role of AMPA receptor nano-organization and dynamic in the properties of synaptic transmission.
Benjamin Compans, Daniel Choquet, Eric Hosy
Neurophoton. 2016-11-15
10.1117/1.nph.3.4.041811

The Munc18-1 domain 3a hinge-loop controls syntaxin-1A nanodomain assembly and engagement with the SNARE complex during secretory vesicle priming.
Ravikiran Kasula, Ye Jin Chai, Adekunle T. Bademosi, Callista B. Harper, Rachel S. Gormal, Isabel C. Morrow, Eric Hosy, Brett M. Collins, Daniel Choquet, Andreas Papadopulos, Frédéric A. Meunier
J Cell Biol. 2016-09-19
10.1083/jcb.201508118

P2X-mediated AMPA receptor internalization and synaptic depression is controlled by two CaMKII phosphorylation sites on GluA1 in hippocampal neurons.
Johan-Till Pougnet, Benjamin Compans, Audrey Martinez, Daniel Choquet, Eric Hosy, Eric Boué-Grabot
Sci Rep. 2016-09-14
10.1038/srep31836

Synaptic adhesion molecule IgSF11 regulates synaptic transmission and plasticity.
Seil Jang, Daeyoung Oh, Yeunkum Lee, Eric Hosy, Hyewon Shin, Christoph van Riesen, Daniel Whitcomb, Julia M Warburton, Jihoon Jo, Doyoun Kim, Sun Gyun Kim, Seung Min Um, Seok-kyu Kwon, Myoung-Hwan Kim, Junyeop Daniel Roh, Jooyeon Woo, Heejung Jun, Dongmin Lee, Won Mah, Hyun Kim, Bong-Kiun Kaang, Kwangwook Cho, Jeong-Seop Rhee, Daniel Choquet, Eunjoon Kim
Nat Neurosci. 2015-11-23
10.1038/nn.4176

SR-Tesseler: a method to segment and quantify localization-based super-resolution microscopy data.
Florian Levet, Eric Hosy, Adel Kechkar, Corey Butler, Anne Beghin, Daniel Choquet, Jean-Baptiste Sibarita
Nat Methods. 2015-09-07
10.1038/nmeth.3579

Mobility of calcium channels in the presynaptic membrane.
Romy Schneider, Eric Hosy, Johannes Kohl, Julia Klueva, Daniel Choquet, Ulrich Thomas, Andreas Voigt, Martin Heine
Neuron. 2015-05-01
10.1016/j.neuron.2015.03.050

Glutamate-induced AMPA receptor desensitization increases their mobility and modulates short-term plasticity through unbinding from Stargazin.
Audrey Constals, Andrew C. Penn, Benjamin Compans, Estelle Toulmé, Amandine Phillipat, Sébastien Marais, Natacha Retailleau, Anne-Sophie Hafner, Françoise Coussen, Eric Hosy, Daniel Choquet
Neuron. 2015-02-01
10.1016/j.neuron.2015.01.012

Super-resolved and dynamic imaging of membrane proteins in plant cells reveal contrasting kinetic profiles and multiple confinement mechanisms.
Eric Hosy, Alexandre Martinière, Daniel Choquet, Christophe Maurel, Doan-Trung Luu
Molecular Plant. 2015-02-01
10.1016/j.molp.2014.10.006

Super-resolved and dynamic imaging of membrane proteins in plant cells reveal contrasting kinetic profiles and multiple confinement mechanisms.
E. Hosy, A. Martiniere, D. Choquet, C. Maurel, D.-T. Luu
Molecular Plant. 2014-10-24
10.1093/mp/ssu123

ATP P2X receptors downregulate AMPA receptor trafficking and postsynaptic efficacy in hippocampal neurons.
Johan-Till Pougnet, Estelle Toulme, Audrey Martinez, Daniel Choquet, Eric Hosy, Eric Boué-Grabot
Neuron. 2014-07-01
10.1016/j.neuron.2014.06.005

Organization and dynamics of AMPA receptors inside synapses-nano-organization of AMPA receptors and main synaptic scaffolding proteins revealed by super-resolution imaging.
Eric Hosy, Corey Butler, Jean-Baptiste Sibarita
Current Opinion in Chemical Biology. 2014-06-01
10.1016/j.cbpa.2014.05.017

Synaptically released matrix metalloproteinase activity in control of structural plasticity and the cell surface distribution of GluA1-AMPA receptors.
Zsuzsanna Szepesi, Eric Hosy, Blazej Ruszczycki, Monika Bijata, Marta Pyskaty, Arthur Bikbaev, Martin Heine, Daniel Choquet, Leszek Kaczmarek, Jakub Wlodarczyk
PLoS ONE. 2014-05-22
10.1371/journal.pone.0098274

The unusual stoichiometry of ADP activation of the KATP channel.
Eric Hosy, Michel Vivaudou
Front. Physiol.. 2014-01-01
10.3389/fphys.2014.00011

Investigating AMPA receptor diffusion and nanoscale organization at synapses with high-density single-molecule tracking methods
Audrey Constals, Eric Hosy, Daniel Choquet
Neuromethods. 2014-01-01
10.1007/978-1-4614-9179-8_4

Single-molecule imaging of the functional crosstalk between surface NMDA and dopamine D1 receptors.
L. Ladepeche, J. P. Dupuis, D. Bouchet, E. Doudnikoff, L. Yang, Y. Campagne, E. Bezard, E. Hosy, L. Groc
Proceedings of the National Academy of Sciences. 2013-10-14
10.1073/pnas.1310145110

Super-resolution imaging reveals that AMPA receptors inside synapses are dynamically organized in nanodomains regulated by PSD95.
D. Nair, E. Hosy, J. D. Petersen, A. Constals, G. Giannone, D. Choquet, J.-B. Sibarita
Journal of Neuroscience. 2013-08-07
10.1523/jneurosci.2381-12.2013

Heterogeneity of AMPA receptor trafficking and molecular interactions revealed by superresolution analysis of live cell imaging.
N. Hoze, D. Nair, E. Hosy, C. Sieben, S. Manley, A. Herrmann, J.-B. Sibarita, D. Choquet, D. Holcman
Proceedings of the National Academy of Sciences. 2012-10-03
10.1073/pnas.1204589109

High-content super-resolution imaging of live cell by uPAINT.
Grégory Giannone, Eric Hosy, Jean-Baptiste Sibarita, Daniel Choquet, Laurent Cognet
Nanoimaging. 2012-09-18
10.1007/978-1-62703-137-0_7

Neurexin-neuroligin adhesions capture surface-diffusing AMPA receptors through PSD-95 scaffolds.
M. Mondin, V. Labrousse, E. Hosy, M. Heine, B. Tessier, F. Levet, C. Poujol, C. Blanchet, D. Choquet, O. Thoumine
Journal of Neuroscience. 2011-09-21
10.1523/jneurosci.6439-10.2011

SK2 channel expression and function in cerebellar Purkinje cells.
Eric Hosy, Claire Piochon, Eva Teuling, Lorenzo Rinaldo, Christian Hansel
The Journal of Physiology. 2011-07-15
10.1113/jphysiol.2011.205823

Intrinsic plasticity complements long-term potentiation in parallel fiber input gain control in cerebellar Purkinje cells.
A. Belmeguenai, E. Hosy, F. Bengtsson, C. M. Pedroarena, C. Piochon, E. Teuling, Q. He, G. Ohtsuki, M. T. G. De Jeu, Y. Elgersma, C. I. De Zeeuw, H. Jorntell, C. Hansel
Journal of Neuroscience. 2010-10-13
10.1523/jneurosci.3226-10.2010

Dynamic superresolution imaging of endogenous proteins on living cells at ultra-high density.
Gregory Giannone, Eric Hosy, Florian Levet, Audrey Constals, Katrin Schulze, Alexander I. Sobolevsky, Michael P. Rosconi, Eric Gouaux, Robert Tampé, Daniel Choquet, Laurent Cognet
Biophysical Journal. 2010-08-01
10.1016/j.bpj.2010.06.005

Purkinje cell-specific knockout of the protein phosphatase PP2B impairs potentiation and cerebellar motor learning.
M. Schonewille, A. Belmeguenai, S.K. Koekkoek, S.H. Houtman, H.J. Boele, B.J. van Beugen, Z. Gao, A. Badura, G. Ohtsuki, W.E. Amerika, E. Hosy, F.E. Hoebeek, Y. Elgersma, C. Hansel, C.I. De Zeeuw
Neuron. 2010-08-01
10.1016/j.neuron.2010.07.009

Impact of disease-causing SUR1 mutations on the KATP channel subunit interface probed with a rhodamine protection assay.
Eric Hosy, Julien P. Dupuis, Michel Vivaudou
J. Biol. Chem.. 2009-11-20
10.1074/jbc.m109.043307

Chicoric acid, a new compound able to enhance insulin release and glucose uptake.
Didier Tousch, Anne-Dominique Lajoix, Eric Hosy, Jacqueline Azay-Milhau, Karine Ferrare, Céline Jahannault, Gérard Cros, Pierre Petit
Biochemical and Biophysical Research Communications. 2008-12-01
10.1016/j.bbrc.2008.09.088

Heteromerization of Arabidopsis Kv channel alpha-subunits: Data and prospects.
Linda Jeanguenin, Anne Lebaudy, Jérôme Xicluna, Carine Alcon, Eric Hosy, Geoffrey Duby, Erwan Michard, Benoît Lacombe, Ingo Dreyer, Jean Baptiste Thibaud
Plant Signaling & Behavior. 2008-09-01
10.4161/psb.3.9.6209

Heteromerization of Arabidopsis Kv channel alpha-subunits: Data and prospects.
Linda Jeanguenin, Anne Lebaudy, Jérôme Xicluna, Carine Alcon, Eric Hosy, Geoffrey Duby, Erwan Michard, Benoît Lacombe, Ingo Dreyer, Jean Baptiste Thibaud
Plant Signaling & Behavior. 2008-09-01
10.4161/psb.3.9.6209

Heteromeric K+ channels in plants.
Anne Lebaudy, Eric Hosy, Thierry Simonneau, Hervé Sentenac, Jean-Baptiste Thibaud, Ingo Dreyer
Plant J. 2008-06-01
10.1111/j.1365-313x.2008.03479.x

Plant adaptation to fluctuating environment and biomass production are strongly dependent on guard cell potassium channels.
Anne Lebaudy, Alain Vavasseur, Eric Hosy, Ingo Dreyer, Nathalie Leonhardt, Jean-Baptiste Thibaud, Anne-Aliénor Véry, Thierry Simonneau, Hervé Sentenac
PNAS. 2008-03-26
10.1073/pnas.0709732105

AtKC1, a conditionally targeted Shaker-type subunit, regulates the activity of plant K+ channels.
Geoffrey Duby, Eric Hosy, Cécile Fizames, Carine Alcon, Alex Costa, Hervé Sentenac, Jean-Baptiste Thibaud
The Plant Journal. 2008-01-01
10.1111/j.1365-313x.2007.03324.x

CFTR inhibition by glibenclamide requires a positive charge in cytoplasmic loop three.
Patricia Melin, Eric Hosy, Michel Vivaudou, Frédéric Becq
Biochimica et Biophysica Acta (BBA) - Biomembranes. 2007-10-01
10.1016/j.bbamem.2007.05.013

Remodelling of the SUR-Kir6.2 interface of the KATP channel upon ATP binding revealed by the conformational blocker rhodamine 123.
Eric Hosy, Renaud Dérand, Jean Revilloud, Michel Vivaudou
The Journal of Physiology. 2007-06-25
10.1113/jphysiol.2007.134288

A procedure for localisation and electrophysiological characterisation of ion channels heterologously expressed in a plant context.
E Hosy, G Duby, A-A Véry, A Costa, H Sentenac, J-B Thibaud
Plant Methods. 2005-01-01
10.1186/1746-4811-1-14

The Arabidopsis outward K+ channel GORK is involved in regulation of stomatal movements and plant transpiration.
E. Hosy, A. Vavasseur, K. Mouline, I. Dreyer, F. Gaymard, F. Poree, J. Boucherez, A. Lebaudy, D. Bouchez, A.-A. Very, T. Simonneau, J.-B. Thibaud, H. Sentenac
Proceedings of the National Academy of Sciences. 2003-04-01
10.1073/pnas.0733970100